Sydney (dpa) – It seems too good to be true: a treatment for the
brain-wasting disease Alzheimer’s that doctors could be prescribing
in just five years’ time.
But it is a prospect that researchers at Sydney University are
holding out to the 250,000 Australians who have contracted what is
the country’s most common form of dementia.
The scientists, working under Jurgen Gotz at the university’s
Brain and Mind Researcher Institute, claim the interaction of two
proteins in an otherwise healthy brain cell is the origin of
In experiments with mice, the team stopped the interaction by
introducing other proteins into brains cells through injections.
“We’ve shown we can prevent the development of Alzheimer’s and
that’s never been done before,” Gotz said. “The next step is to
develop compounds that are easier to administer, either orally or
intravenously. We could have treatments in five years because this is
targeting the underlying biology of the disease – not the symptoms.”
The research paper is published in the journal Cell.